Integrin Alpha V + Beta 6 Antibody bs-5791R from Bioss Inc.

Description

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha-v beta-6 is upregulated in cancers and during tissue remodelling but is absent from resting adult tissues. Integrin alpha-v beta-6 promotes invasion and correlates with poor survival and therefore makes a promising therapeutic target

Product Specs
ItemIntegrin Alpha V + Beta 6 Antibody
CompanyBioss Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberbs-5791R
TargetIntegrin Alpha V + Beta 6
Conjugate/TagUnconjugated
ClonalityPolyclonal
IsotypeIgG
ImmunogenKLH conjugated peptide, human Integrin Alpha V + Beta 6
Quantity100ul
ReactivityHuman, Mouse, Rat
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
HostRabbit
Brand/TrademarkBioss
ApplicationsWB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Concentration1ug/ul
Antibody TypePrimary Antibody
NCBI Gene AliasesAI1H, VTNR, CD51, VNRA, MSK8
NCBI Full Gene Nameintegrin subunit alpha V, integrin subunit beta 6
Tissuexenograft SAS tumors, Pancreas
PurityProtein A purified

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Bioss Inc.

400 Trade Center, Suite 2990

Woburn, Massachusetts 01801

United States

Phone: 800.501.7654 (Toll free)
Phone: +1.781.569.5821 (International)

Email: info@biossusa.com
orders@biossusa.com
support@biossusa.com
business@biossusa.com

Company Profile

Website: www.biossusa.com

(1) Nintedanib-αVβ6 Integrin Ligand Conjugates Reduce TGFβ-Induced EMT in Human Non-Small Cell Lung CancerInternational journal of molecular sciencesJanuary 12, 2023Andreucci E, Bugatti K, Peppicelli S, Ruzzolini J, Lulli M, Calorini L, Battistini L, Zanardi F, Sartori A, Bianchini F.(cytofluorimetry buffer). After blocking, cells were incubated with 1 μg/20 μL buffer of anti-αvβ6 (Bioss bs 5791R, Woburn, MA, USA, as suggested dilution 1:20) (anti-human/mouse/rat) for 1 h at 4 °C, followed by 1

(2) Recombinant truncated latency-associated peptide alleviates liver fibrosis in vitro and in vivo via inhibition of TGF-β/Smad pathwayMolecular MedicineDecember 1, 2022Xudong Song et al.The following primary antibodies from Bioss Antibodies (Peking, China): Integrin Alpha V + β6 (Cat.bs-5791R); The following primary antibodies from Cell Signaling Technology (Danvers, USA): Smad2 (Cat.3122),

(3) Inhibition of β-catenin signaling attenuates arteriovenous fistula thickening in mice by suppressing myofibroblastsMolecular MedicineDecember 1, 2022Chung-Te Liu et al.#17819), CD31 (Abcam, ab28364), vimentin (Cell Signaling, 5741), integrin subunit β6 (ITGB6, Bioss, bs-5791R), β-catenin (Cell Signaling, 8480), axin2 (Abcam, ab32197), c-myc (Abcam, ab32072), Tie2 (Bioss, bs-1300R).

(4) Mechanical stress determines the configuration of TGFβ activation in articular cartilageNature communicationsMarch 17, 2021Zhen G, Guo Q, Li Y, Wu C, Zhu S, Wang R, Guo XE, Kim BC, Huang J, Hu Y, et al.sections with primary antibodies to mouse pSmad2/3 (sc-11769, Santa Cruz Biotechnology, 1:100), αVβ6 (BS-5791R, Bioss Antibodies, Woburn, MA, RRID:AB_11042026, 1:100), αVβ3 (BS-1310R, Bioss Antibodies, RRID: AB_10854294,

(5) Clinical Translation of a ⁶⁸Ga-Labeled Integrin α_vβ₆–Targeting Cyclic Radiotracer for PET Imaging of Pancreatic CancerJournal of Nuclear MedicineOctober 1, 2020Xun Feng et al.retrieved by microwave, tumor tissues were incubated with rabbit antihuman integrin avb6 antibody (bs-5791r; Bioss) overnight at 4C. Afterward, tumor sections were incubated with a horseradish peroxidase–conjugated

(6) Clinical Significance of C-X-C Motif Chemokine Receptor 4 and Integrin αvβ6 Expression in Breast CancerJournal of Breast CancerApril 6, 2020Hongshan Huang, Mengci Yuan, Shuang-Ling Wu, Jinling Ba, Xinmiao Yu, Xiaoyun Mao, Feng Jinwith primary antibodies against CXCR4 (ab1670, 1:200 dilution; Abcam, Cambridge, UK) or integrin αvβ6 (bs-5791R, 1: 400; Bioss Inc., Beijing, China) at 4°C overnight. As negative controls, sections were incubated

(7) Effect of human amniotic epithelial cells on pro-fibrogenic resident hepatic cells in a rat model of liver fibrosisJournal of cellular and molecular medicineFebruary 1, 2018Cargnoni A, Farigu S, Cotti Piccinelli E, Bonassi Signoroni P, Romele P, Vanosi G, Toschi I, Cesari V, Barros Sant'Anna L, Magatti M, et al.

(8) A near-infrared phthalocyanine dye-labeled agent for integrin avß6-targeted theranostics of pancreatic cancerBiomaterialsJune 1, 2015Duo Gao, Liquan Gao, Chenran Zhang, Hao Liu, Bing Jia, Zhaohui Zhu, Fan Wang, Zhaofei Liu

(9) Scutellarin inhibits the growth and invasion of human tongue squamous carcinoma through the inhibition of matrix metalloproteinase-2 and -9 and αvβ6 integrinInternational Journal of OncologyMay 1, 2013HAIXIA LI, DAYONG HUANG, ZHONGXIUZI GAO, YAN CHEN, LINA ZHANG, JINHUA ZHENG

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Molecular Medicine

Molecular Medicine

Integrin Alpha V + Beta 6 Antibody from Bioss Inc.

Description

Bioss Inc.

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Integrin Alpha V + Beta 6 Antibody from Bioss Inc.

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